What is the gold standard test for hemoglobin levels in blood donors?

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AIIMS NORCET 7 Prelims Memory Based Paper 2024
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  1. Hematocrit test
  2. Complete blood count (CBC)
  3. Hemoglobin electrophoresis
  4. Serum iron test

Answer (Detailed Solution Below)

Option 2 : Complete blood count (CBC)
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AIIMS NORCET 8: Cardiovascular System
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Correct Answer: Complete blood count (CBC)
Rationale:
  • A Complete Blood Count (CBC) is the gold standard test for assessing hemoglobin levels in blood donors. The CBC provides a comprehensive overview of the components of blood, including red blood cells, white blood cells, and platelets.
  • The hemoglobin concentration is a critical parameter measured in a CBC. Hemoglobin is the protein in red blood cells responsible for transporting oxygen throughout the body. Adequate hemoglobin levels are essential for ensuring that the blood donor is healthy and capable of tolerating blood donation.
Explanation of Other Options:
Hematocrit test
  • Rationale: The hematocrit test measures the proportion of red blood cells in the blood. While it provides useful information, it does not directly measure hemoglobin levels. Hemoglobin concentration provides more specific information about the oxygen-carrying capacity of the blood.
Hemoglobin electrophoresis
  • Rationale: Hemoglobin electrophoresis is a test used to identify different types of hemoglobin and diagnose hemoglobinopathies, such as sickle cell anemia or thalassemia. It is not routinely used for measuring hemoglobin levels in blood donors.
Serum iron test
  • Rationale: The serum iron test measures the amount of iron in the blood. While iron is a key component of hemoglobin, this test does not directly measure hemoglobin levels. It is often used to diagnose iron deficiency anemia rather than to assess eligibility for blood donation.
Conclusion:
  • Among the given options, a Complete Blood Count (CBC) is the most accurate and comprehensive test for measuring hemoglobin levels in blood donors. It provides crucial information to ensure that donors have adequate hemoglobin levels to safely donate blood.
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