Prader-Willi syndrome (PWS) is characterized by which of the following symptoms?
A. Insatiable appetite

B. Obesity

C. Growth hormone deficiency

D. Intellectual disability

E. Hyperthyroidism

Choose the correct answer from the options given below:

The correct answer is 'A, B, C and D Only'

Key Points

• Prader-Willi syndrome (PWS):
  • Prader-Willi syndrome is a rare genetic disorder that affects many parts of the body and is recognized by a variety of distinct symptoms.
  • Insatiable appetite (A): One of the hallmark symptoms of PWS is an insatiable appetite, which can lead to chronic overeating and obesity.
  • Obesity (B): Due to the insatiable appetite and lack of satiety, individuals with PWS often develop obesity, which can lead to other health complications.
  • Growth hormone deficiency (C): Growth hormone deficiency is common in individuals with PWS and can contribute to their short stature and obesity.
  • Intellectual disability (D): Most individuals with PWS have some degree of intellectual disability, ranging from mild to moderate.

Additional Information

• Hyperthyroidism (E):
  • Hyperthyroidism is not typically associated with PWS. In fact, individuals with PWS are more likely to have hypothyroidism (underactive thyroid) rather than hyperthyroidism (overactive thyroid).
• Diagnosis and Management:
  • PWS is usually diagnosed through genetic testing. Management involves a multidisciplinary approach including dietary management to control weight, hormone therapy, and support for intellectual and developmental disabilities.